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KMID : 1059520130570040476
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Journal of the Korean Chemical Society
2013 Volume.57 No. 4 p.476 ~ p.482
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One Pot Synthesis of Bioactive Novel Cyanopyridones
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Khokhani Kamlesh M.
Khatri Taslimahemad T.
Patel Praful
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Abstract
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Cyanopyridone was prepared by the condensation of cyanoacetamide, substituted arylaldehydes and malononitrile in presence of pipyridine. The structure of the synthesized compound CP 1-20 was assigned on the basis of elemental analysis, IR, 1H-NMR and mass spectroscopy. These compounds were also screened for antimicrobial activity. The Minimum Inhibitory Concentration (MIC) of all the synthesized compounds was compared with standard drugs.
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KEYWORD
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Cyanopyrimidones, Cyanoacetamide, Antimicrobial activity, Malononitrile, Pipyridine
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